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Patients and methods This study was performed at academic ce
2019-08-29
Patients and methods This study was performed at 3 academic centers (Chung-Ang University YongSan Hospital, Soonchunhyang University Hospital, and Chung-Ang University Hospital) in Seoul, Korea, from November 2008 to November 2010. The study protocol was approved by the institutional review boards
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Loratadine br Progestogens and autoimmune diseases br Conclu
2019-08-29
Progestogens and autoimmune diseases Conclusion Take-home messages Introduction The benefits of breastfeeding for both women and their infants are considerable [1], [2], [3]. The World Health Organization (WHO) recommends infants breastfeed exclusively during the first months of life [4]
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br Introduction Phoenixin PNX is a
2019-08-29
Introduction Phoenixin (PNX) is a recently discovered peptide produced mainly in hypothalamus by proteolytic cleavage of a small integral membrane protein 20 (Smim20) [1]. The most important endogenous active isoforms of PNX are amided peptides, composed of 14 and 20 perhexiline [2]. Previous da
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However with regard to the
2019-08-29
However, with regard to the involvement of PEP in neoplastic processes, few studies and restricted to a very limited number of different tumors have been carried out [4], [18], [19]. Therefore, in order to ascertain the possible role of this enzyme in pathological proliferative tissues, in the prese
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Pyruvate dehydrogenase multienzyme complex PDHc catalyzes th
2019-08-29
Pyruvate dehydrogenase multienzyme complex (PDHc) catalyzes the oxidative decarboxylation of pyruvate, and subsequently acetylates coenzyme A (CoA) to acetyl-CoA during the tricarboxylic a66 metabolic pathway using thiamine diphosphate (ThDP) and Mg2+ as cofactors. PDHc poses a key role in cyanobact
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br Progestogens and venous thromboembolism
2019-08-28
Progestogens and venous thromboembolism: clinical data Progestogens and haemostatis: biological studies For many years, the effect of HT on haemostatis has been largely investigated in observational studies as well as in high evidence level studies among users of oral and transdermal estrogens
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Curcumin is found safe in several human studies Chainani
2019-08-28
Curcumin is found safe in several human studies (Chainani-Wu, 2003; Cheng et al., 2001; Dcodhar et al., 2013), in contrary, the toxicity of curcumin has also been reported under some specific conditions (Burgos-Morón et al., 2010). Moreover, it tgx mass was also reported that curcumin induced some
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Repulsive interactions towards undesirable substrates are ar
2019-08-28
Repulsive interactions towards undesirable substrates are arguably a very efficient means to implement specificity [8]. In particular, it could be assumed that discrimination against a substrate that is larger than the cognate substrate may be achieved easily by restricting the active site and explo
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In the course of this
2019-08-28
In the course of this study, K+PFOS did not appear to have any effect on the thyroid parameters evaluated (H&E histology, follicular epithelial cell proliferation, and follicular epithelial apoptosis). This is an interesting observation considering the fact that treatment with K+PFOS resulted in act
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br Materials and Methods br Results br Discussion
2019-08-28
Materials and Methods Results Discussion Viral infection of eukaryotic SB939 pathway activate signaling pathways both via specific interaction with pattern recognition receptors (TLRs, RIG-I, MDA5) and more nonspecific mechanisms such as accumulation of newly synthesized viral glycoproteins
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br Development of the double strand break
2019-08-28
Development of the double strand break repair model for meiotic recombination Meiotic recombination was first described by Frans Alfons Janssens using streptozocin in the salamander Batracoseps attenuatus in 1909 [21] and then further elaborated at the genetic level in Drosophila by Thomas H. Mor
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Direct coupling between DNA methyltransferase enzymes and po
2019-08-28
Direct coupling between DNA methyltransferase enzymes and posttranslational modifications on histone proteins has been observed in mammals. For example, DNMT3A recognizes unmodified H3 through an ATRX-DNMT3-DNMT3L (ADD) domain, and its activity is inhibited by methylation of H3 at K4 (Li et al., 201
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Several authors have been pursuing the aim of
2019-08-28
Several authors have been pursuing the aim of finding good performing organic solvent compatible adsorbers useful in the context of API purification [[10], [11], [12], [13], 22, 23]. For sulfonate GTIs, scavenging nucleophilic resins [22, 23] or molecular imprinted polymers (MIPs) [10] have been exp
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Despite its significance in tumor suppression the molecular
2019-08-28
Despite its significance in tumor suppression, the molecular mechanism by which DAPK is regulated and its interplay with other tumor suppressors and oncoproteins have not been completely unraveled. Although primarily regulated by CaM binding (Cohen et al., 1997), DAPK activity can also be modulated
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In general up to date no study has considered thermodynamic
2019-08-28
In general, up to date, no study has considered thermodynamic modeling to estimate the L-Carnitine inner salt and of SO2 by different DESs. Since experimental measurements are time consuming and expensive, general and accurate theoretical models are vital to estimate SO2 solubilities in different D
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